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A recent pilot study conducted by the research team showed that in patients who received CUHK's microbiome immunity formula SIM01 for four weeks, over 90% of them did not develop long COVID up to a year of follow-up.
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The research team showed that the efficacy of SinoVac and BioNTech correlated with a unique bacterium, Bifidobacterium adolescentis. People who lacked Bifidobacterium adolescentis in their gut had a suboptimal antibody response both vaccines.
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"Long COVID", known as post-COVID syndrome, are signs and symptoms that develop during or following an infection including COVID-19 which continue for more than 12 weeks and are not explained by an alternative diagnosis.
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Preliminary study in the laboratory using blood samples from individuals who have received COVID-19 vaccine showed that addition of a beneficial bacteria consortia developed by CUHK is effective in reducing inflammatory cytokines and enhancing antibody level.
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The benefit of G-NiiB Immunity formula is not limited to COVID-19 patients. In 1000 healthy individuals in Hong Kong, almost 40% had imbalance of the gut bacteria (a marker of impaired immunity against infections), which could predispose them to infections including COVID-19.
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COVID-19 patients who received the microbiome immunity formula achieved complete symptom resolution, reduced proinflammatory markers, had increased favourable bacteria; and developed neutralising antibody.
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The human gut microbiome is relevant to COVID-19. The intestinal micro-ecology dominates our immunity. When this micro-ecology is out of balance, we are vulnerable to viruses.
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