novel virus and the microbiome

The human gut microbiome is relevant to the novel virus infection. The intestinal micro-ecology dominates our immunity. When this micro-ecology is out of balance, we are vulnerable to viruses.

Gut microbiota, which is a fine balance between good and bad bacteria, regulates our immune system. Imbalance in gut microbiota (dysbiosis) will make us susceptible to infections.

Gut Microbiota Imbalance

Healthy

Mild

Moderate

Serious

Types of micro-ecology, decrease in number, imbalance of intestinal micro-ecology

The Centre for Gut Microbiota Research of The Chinese University of Hong Kong discovered for the first time worldwide in June 2020 that novel virus patients had missing good bacteria affecting their immunity against infections. 

The World's First Proof

Using metagenomic sequencing and machine learning, a research team from the Chinese University of Hong Kong School of Medicine found:

Healthy people (left), novel virus patients with mild symptoms (middle), novel virus patients with severe symptoms (right)
Novel virus patients with severe gut microbiome imbalance
Novel virus patients with severe gut microbiome imbalance
Symptom severity correlates with gut microbiome imbalances
Symptom severity correlates with gut microbiome imbalances

There is also sufficient literature to support that lack of these good bacteria will reduce immunity. These findings indicate that novel virus infection can cause major changes in the human microbial flora, and the microbial flora may help the diagnosis, treatment and prevention of novel virus infection.

International authoritative medical journal of gastroenterology shows that healthy intestinal microecology continues to be unbalanced after recovery
Novel virus infection causes gut microbiome imbalance

MORECU Medicine Develops a Probiotic Formula to Target Imbalance in Gut Microbiota in novel virus

https://www.cpr.cuhk.edu.hk/en/press/cu-medicine-develops-a-probiotic-formula-to-target-imbalance-in-gut-microbiota-in-novel-virus/