G-NiiB Immunity + (SIM01 ) - GenieBiome Limited | Rejuvenate Your Unique Microbiome With Science

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G-NiiB Immunity

Microbiome Precision Formulation (SIM01)

3+3 Vibrant Probiotics and Prebiotics Golden Ratio

Contain Bifidobacterium Adolescentis

Immunity Boosting Proved by Clinical Research

G-NiiB Immunity + (SIM01) is a unique microbiome Immunity formula that can be used as a dietary supplement. This formula uses big data to select ideal naturally occurring live bacteria, with patented microencapsulated technology from Italy to enhance live bacteria survival, and is clinically shown to be effective and safe in local novel virus patients. G-NiiB obtained exclusive patent licensing from the Chinese University of Hong Kong;

Value Proposition

Enhance the safety and efficiency of vaccine

(Related Study 1)

Speed up the recovery after disease.

Boost the ability of making antibody.

(Related Study 2)

Prevent and relieve “Post Novel Virus Conditions”

(Related Study 3)

Relieve

Constipation

Diarrhoea

Gastro-Intestinal Discomfort

Skin Irritation

Supplement for Asians

In accordance with Metagenomics and Asian Big Data. Carefully chosen 3 Vibrant Probiotics from Italy - Bifidobacteria

3+3 Vibrant Probiotics and Prebiotics Golden Ratio

3 Bifidobacterium Probiotics Blend

Contain Bifidobacterium adolescentis and Bifidobacterium longum. Balances gut microbiome, boosts immunity, and promote other beneficial microbes growth

3 Precise Prebiotic Blend

Provide the most suitable nutrition for bifidobacteria

Contain Bifidobacterium adolescentis and Bifidobacterium longum. Balances gut microbiome, boosts immunity, and promote other beneficial microbes growth

Provide the most suitable nutrition for bifidobacteria

Patented microencapsulation technology from Italy

Protect live probiotic against gastric acid and ensure colonizing in the gut

Del Piano M. et al. In Vitro Sensitivity of Probiotics to Human Pancreatic Juice. J Clin Gastroenterol. 2008; 42 (3): S170-173.
Charteris WP. et al. Development and application of an in vitro methodology to determine the transit tolerance of potentially probiotic Lactobacillus and Bifidobacterium species in the upper human gastrointestinal tract. J App Microbiol. 1998; 84 (5): 759-768.
Del Piano M. et al. Evaluation of the intestinal colonization by microencapsulated probiotic bacteria in comparison with the same uncoated strains. J Clin Gastroenterol. 2010 Sep; 44 Suppl 1:S42-6.

Related Study

Enhance the safety and efficiency of vaccine

Preliminary study in the laboratory using blood samples from individuals who have received novel virus vaccine showed that addition of a beneficial bacteria consortia developed by The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) is effective in reducing inflammatory cytokines and enhancing antibody level.

In a collaborative research project between CU Medicine and the LKS Faculty of Medicine at The University of Hong Kong (HKUMed), the research team showed that the efficacy of SinoVac and BioNTech correlated with a unique bacterium, Bifidobacterium adolescentis.

(Learn more)

Speed up the recovery after disease. Boost up the ability of making antibody.

Clinical data showed the recovery of novel virus patients who received the microbiome immunity formula (SIM01) outperformed those with standard care in many aspects. These include the achievement of complete symptom resolution; significant reduction of proinflammatory markers in their blood, increase in favourable bacteria in their stool and development of neutralising antibody.

(Learn more)

Amid the third wave of novel virus outbreak in Hong Kong, the CU Medicine team recruited 55 hospitalised patients with novel virus; 25 patients were treated with the microbiome immunity formula and 30 received standard care. Key findings are as follow:

100% of patients treated with the microbiome immunity formula achieved complete resolution of symptoms compared with half in the control group by week 2.
88% of patients in the microbiome immunity formula group developed neutralizing antibody compared with 63% in the control group.
The blood level of pro-inflammatory cytokines was significantly reduced in the microbiome immunity formula group, indicating that inflammation was under control.
The levels of favourable bacteria recovered from stool in patients receiving the microbiome immunity formula was significantly increased, suggesting that the formula could restore gut dysbiosis.

And to evaluate the extent of dysbiosis in the general population, CU Medicine studied 1,000 subjects in Hong Kong aged between 18 and 83 and found that almost 40% of them had significant dysbiosis (i.e., impaired immunity) comparable to that of novel virus patients.

Read More﹕40% of Hong Kong People Show Gut Dysbiosis Comparable to that of novel virus Patients CUHK Microbiome Immunity Formula Hastens Recovery of novel virus Patients and Offers Hope to Boost Immunity

https://www.cpr.cuhk.edu.hk/en/press/40-of-hong-kong-people-show-gut-dysbiosis-comparable-to-that-of-novel-virus-patientscuhk-microbiome-immunity-formula-hastens-recovery-of-novel-virus-patients-andoffers-hope-to-boost-immunity/

Read More﹕Gut microbiota-derived synbiotic formula (SIM01) as a novel adjuvant therapy for novel virus: An open-label pilot study

https://onlinelibrary.wiley.com/doi/10.1111/jgh.15796

Read More﹕CU Medicine Develops a Probiotic Formula to Target Imbalance in Gut Microbiota in novel virus

https://www.cpr.cuhk.edu.hk/tc/press/cu-medicine-develops-a-probiotic-formula-to-target-imbalance-in-gut-microbiota-in-novel-virus

Prevent and relieve “Post Novel Virus Conditions”

A recent study by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) discovered that composition of gut microorganisms (microbiota) in novel virus patients is very different from uninfected individuals and is linked to disease severity. novel virus patients lack certain good bacteria known to regulate their immune system and the abnormal gut microbiota (dysbiosis) persists after clearance of the virus, which could contribute to lingering symptoms, known as “Post Novel Virus Conditions ”. The study results suggest gut microbiome may influence the severity of novel virus as well as the magnitude of the immune response to the infection. Clinical management not only should aim at clearing the virus but also restoring the abnormal gut microbiota. The findings have been published in the international journal Gut and its global press release.

(Learn more)

Product Specification

7 sachet / package

14 sachet / package

28 sachet / package

Suggested Use

One sachet daily. Consume directly, or mix in 100-200ml water, non-frizzy or non-alcoholic drinks or food (below 45°C). It can be taken at any time of the day but is best consumed with a meal.

Also suitable for children aged 2 above, pregnant and breastfeeding women

Best consume with

Yogurt

Juice

Cereal

Room-Temperature Beverages

Caution

Store in a cool, dry place and avoid sunlight.
The product contains traces of milk. People with lactose intolerance or those aged below 2 are recommended to consult a physician before use.

Food Supplement

No Artificial Flavours and Colourings

Gluten-Free

Non-GMO

FAQ

What is gut microbiota?

Gut microbiota, which is the ecosystem of microorganisms in our gut, is a major determinant of human health. Emerging evidence indicates that the gut microbiota plays an important role in many conditions such as overweight, overreaction of the body's immune system, skin irritation, metabolic syndrome, cardiovascular health, mental health, gut serious illness, liver serious illness and malnutrition in muscle, etc.

Why is the gut microbiota relevant to our immunity?

The gut microbiota regulates our immune system against infections. A number of recent landmark studies from The Chinese University of Hong Kong (CUHK) discovered that patients with novel virus suffered from severe imbalance of gut microbiota (dysbiosis) with a decrease in beneficial bacteria which may contribute to susceptibility to novel virus infections and adverse clinical outcomes.

How is this microbiome immunity formula different from other probiotics?

Our product is based on innovative discoveries exclusively licensed from The Chinese University of Hong Kong. This microbiome formula is derived from big data analysis of novel virus patients and the healthy population. A clinical study by CUHK showed that significantly more novel virus patients who received the microbiome immunity formula had complete symptom resolution, reduced proinflammatory markers, increased favourable gut bacteria and neutralizing antibody, compared with subjects who did not have the formula.

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How will this product benefit me and my family?

The benefit of this microbiome immunity formula is not limited to only novel virus patients. In a separate study of 1,000 healthy people in Hong Kong, almost 40% showed significant dysbiosis and hence impaired immunity similar to that of novel virus patients. This formula has the potential to boost your immunity against emerging infections.

What are probiotics?

A probiotic is a living microorganism, which improve our intestinal microbial balance; probiotics are non-pathogenic and are mostly can survive in stomach and pass to small bowel. They help to protect against disease and maintain wellbeing.

Our body harbours a great number of bacteria in the gut, especially in our large bowel. Described as our “invisible organ”, not only do these microorganisms help harvesting energy and producing certain nutrients from prebiotics, they also play an important role in immunity and communication with our brain.

What are prebiotics?

Gut bacteria need fuel to live, just like us! What gut bacteria feed on is called prebiotics, “a substrate that is selectively utilized by host microorganisms conferring a health benefit”. These substrates are mostly subset of carbohydrate groups, which remain intact beyond the acidic stomach environment in the digestive tract, and travel down to be served as a fest to the bacteria in the large intestine. Gut bacteria feed on these substrates and produce short chain fatty acids (SCFAS) that have protective effect on our gut health.

What is precise 3+3 formula?

“G-NiiB Immunity + (SIM01)” contains 3 well selected bifidobacteria and 3 specific prebiotics. These 3 specific prebiotics provide the best performance in enhancing the 3 bifidobacteria viability.

Why should i take probiotic supplements when they are available in food?

Probiotics in “G-NiiB Immunity +(SIM01)” are specially protected by a patented technology from Italy, so they are tolerance to heat, oxygen, and gastric juice.

Most of the fermented food contains probiotics, but the type and amount of probiotic vary among in each food so it may not be the best way to fulfil our need. Moreover, as probiotics in food are not protected, they are very venerable to gastric juice and most of them will not make their way to the GUT.

Is it suitable for people with lactose intolerance?

The product contains traces of milk. People with lactose intolerance are recommended to consult a physician before use.

Is it suitable for people with g6pd deficiency?

The product does not contain any substance that is not suitable for people with g6pd deficiency thus the product is suitable for people with g6pd deficiency.

Is it suitable for people with diabetes?

The product only contains a very small amount of sugar which is come from the prebiotics. Recent studies have shown that consumption of prebiotics and probiotics can decrease the fasting blood glucose level. Thus, the product is suitable for people with diabetes.