G-NiiB Immune Kids SIM03 is a unique microbiome formula that can be used as a dietary supplement. This formula uses big data to select ideal naturally occurring live bacteria, with patented microencapsulated technology from Italy to enhance live bacteria survival and is clinically shown to be effective and safe in local children with sensitive skin. This formula is scientifically formulated with exclusive patent licensing and clinically studied by The Faculty of Medicine of a Renowned University in Hong Kong.

Ingredients: Maltodextrin (Prebiotics), Fructooligosaccharides (Prebiotics), Xylitol (Prebiotics), Probiotics Blend developed by the Faculty of Medicine of a Renowed Univeristy in Hong Kong (1 billion CFU/sachet), Calcium Acetate and Zinc Acetate

1. 100% reduction in the number of children with medium sensitive skin: from medium to mild
2. 50% reduction in the number of children with severe sensitive skin: from severe to medium

The SCORAD score is clinically used to evaluate the severity of sensitive skin. It will be scored based on the sensitive skin area, degree of lesions, pruritus and sleep loss. The score is directly proportional to the severity.

Studies have shown that the formula not only significantly reduced the infected area and intensity by 38.9%, but also reduced the sensitivity index from moderate to mild in 100% of children with moderate eczema sensitivity, and improved from severe to moderate in 50% of children with severe eczema sensitivity. The data confirms that the treatment effect increases over time, with the moderately sensitive skin group achieving comprehensive improvement and half of the severely sensitive skin group experiencing effective relief.

*According to the IDQOL (1-3 years old) and CDLQI (4-5 years old) quality of life scores, the assessment items include: itching and scratching, sleepings problems, disturbance in dressing, disturbance in bathing, treatment problems and disturbance in sports activities.

✓ Acetate helps eliminate pathogens, toxins and allergens, preventing cells from infection and invasion.²

✓ Acetate also helps to develop rainbow immunity, and acts as a critical nutrient to coordinate the immune system and inflammation with its anti-inflammatory property.²

Protect live probiotic against gastric acid and ensure colonizing in the gut

G-NiiB utilizes patented microencapsulation technology from Italy to shield beneficial bacteria from gastric acid erosion through a patented coating method. This technology improves the probiotics' survival rate by up to 250% and enhances their intestinal colonization (CFU) by up to five times.

G-NiiB offers a microbiome precision formula containing freeze-dried live, good bacteria with patented microencapsulation technology from Italy , and heat-resistant prebiotics. These ensure sufficient good live bacteria reach the intestine to deliver therapeutic actions and a long shelf-life.

Developed based on the clinical study on sensitive skin in Asian children, comparing a large healthy subject database, G-NiiB Immune Kids SIM03 tailors to the Chinese and Asian microbiome.

G-NiiB Immune Kids SIM03 contains live good bacteria and prebiotics based on accurate and precise AI machine learning results to provide the BEST result and achieve our health goal.

G-NiiB Immune Kids SIM03 utilizes the gut-skin axis to improve children's skin condition from the inside out. Butyrate produced by specific good bacteria helps coordinate the immune system and relieves sensitive skin⁴.

70% of immune cells are present in the gut, and there is an intricate interplay between the gut microbiome and the immune system. Good bacteria play a role in regulating immunity, and those in SIM03 help to develop a diverse rainbow immunity so that the immune system of children can properly respond to the various irritants and allergens encountered during the growth journey.

One sachet daily. Consume directly, or mix in 100-200ml water, non-frizzy or non-alcoholic drinks or food (below 45°C). It can be taken at any time of the day but is best consumed with a meal.

Keep out of reach of children.

If your children are allergic to any of the ingredients in this product, please contact physician before use.

Take the product at least 3 hours before or after taking antibiotics, or as advised by a physician.

1.) How does G-NiiB Immune Kids Formula SIM03 help children improve skin sensitivity problems?

Answer: The SIM03 formula contains a unique combination of Bifidobacterium strains, including Bifidobacterium breve and Bifidobacterium bifidum, selected following an analysis of intestinal microbiota data from Asian children. SIM03 addresses skin issues such as eczema by regulating the balance of intestinal flora.

Research indicates that a deficiency of beneficial bacteria in the intestines predisposes the immune system to allergic reactions, leading to skin inflammation and itching. The beneficial bacteria in SIM03 promote the production of advantageous substances in the intestines, strengthen the intestinal barrier, modulate immune cells, and reduce allergic skin reactions. As a probiotic for kids, it enhances skin condition from the inside out by prioritizing intestinal health.

2.) Are there any side effects from taking Immune Kids Formula SIM03?

Answer: G-NiiB Immune Kids Formula SIM03 is developed and clinically proven by the Faculty of Medicine of a Renowned University in Hong Kong. Its efficacy and safety have been validated through clinical studies, confirming the absence of side effects or dependency.

3.) Is this probiotic for kids easy for children to consume?

Answer: G-NiiB Immune Kids Formula SIM03 is designed with children’s acceptance in mind. It can be directly mixed into cold water, milk, or beverages at room temperature, featuring a nearly neutral taste that is readily accepted by children. Many parents incorporate the powder into plain cheese, applesauce, or mashed bananas, preserving the probiotics' activity. Caution is advised to avoid using hot water for preparation (temperature should not exceed 45°C) and to refrain from adding it to carbonated drinks or fruit sodas.

References

1. Improvement in Sensitive Skin and the Safety of Microbiome Baby Immunity Formula (SIM03) on Childhood Sensitive Skin Development.The Faculty of Medicine, The Chinese University of Hong Kong, 2022. ed.

2. Balmer, Maria Let al. "Memory CD8+ T Cells Bolence Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of infection." Cell metabolism vol. 32,3 (2020): 457-467.e5. doi: 10.1016/j.cmet.2020.07.004

3. Del Piano M. et al. in Vitro Sensitivity of Probiotics to Human Pancreatic Juice. J Clin Gestroenterol 2008; 42 (3): S170-173.

4. Xiao X, Hu X, Yao J, et al. The role of short-chain fatty acids in inflammatory skin diseases. Front Microbiol. 2023;13:1083432. Published 2023 Feb 2. doi:10.3389/fmicb.2022.1083432